The Patent Finder
US

Leukemia Methylation Markers and Uses Thereof

US 10,093,986 Lapsed on the fee record
OverviewFamilyAssignmentsSources & methods

Lapsed Oct 9, 2026 on the fee record · Low confidence

Second maintenance fee unpaid; grace period ended. The USPTO has not yet posted the lapse.

Filed Feb 16, 2017 as application 15/435,174 · Granted Oct 9, 2018
Base term, 20 years from filing
Today
Lapsed Oct 9, 2026
2017 2037
Clock starts
Feb 16, 2017
No longer in force
Oct 9, 2026
Granted
Oct 9, 2018
Term would have run to
Feb 16, 2037
base term after the term ends fee events Updated Nov 14, 2026 · includes USPTO assignment & status data published Nov 14, 2026 and grant & fee data published Nov 10, 2026 (weekly) · how we know
None
Term adjustment
No prosecution delay on this record.
None
Terminal disclaimer
No disclaimer on this record.
1 of 3
Maintenance fees paid
Three maintenance fees fall due, at 3.5, 7.5 and 11.5 years from grant. This counts the ones the record shows paid.
4
Family applications on record here
Applications sharing this one's continuity chain whose file history this site holds. The family may have others.

Its term would have run to Feb 16, 2037: its 20-year base term, with no adjustment for prosecution delay. Confidence: Low. from the record

How we calculated this date

One row per rule, each showing its own input and what it did to the date. A step we could not verify says so instead of resolving itself.
StepInputDate after this stepConfidence
Base term, 20 years from filingClock starts Feb 16, 2017, when this application, 15/435,174, was filedFeb 16, 2037High confidence
Continuity chainEvery parent in the chain resolvedno changeHigh confidence
Patent term adjustmentNone on fileno changeHigh confidence
Terminal disclaimer capNone on recordno cap appliedHigh confidence
Patent term extensionNone on fileno changeHigh confidence
Fee eventsNo fee event states this; the fee state is read from the payments the fee record holds; the fee record shows no payment for this window, and USPTO's status still reads "Patented Case"lapsed Oct 9, 2026Low confidence
Computed term endThe steps above, in orderOct 9, 2026Low confidence

This family

US 10,093,986this patent
Oct 2026
Oct 2026
Application PCT/US2017/040953PCT application
no patent term
no patent term
US 10,829,821In force
Feb 2037
Feb 2037
Application 16/908,572Abandoned
not computed
not computed
The applications whose file history this site holds. The family may have others.

Assignments

Assignment documents as recorded at the USPTO, oldest first, with the reel and frame each was recorded at. A recorded assignment is a filed document, not a statement of current ownership, and the absence of a later one is not evidence that the last one still stands.
RecordedAssignorAssigneeConveyance
May 31, 2018
Reel 45952, frame 536
Zhang, KangThe Regents of the University of CaliforniaAssignment of Assignor's Interest
May 31, 2018
Reel 45952, frame 660
Hou, Rui; Zheng, LianghongYouhealth Biotech, LimitedAssignment of Assignor's Interest
May 19, 2022
Reel 59964, frame 569
Youhealth Biotech, LimitedYouhealth Oncotech, LimitedAssignment of Assignor's Interest
Oct 15, 2024
Reel 68906, frame 59
Youhealth Oncotech, LimitedHelio Health Inc.Assignment of Assignor's Interest

Sources

Google Patents · The patent document at USPTO · Assignment records at USPTO

USPTO account required: This application in Patent Center · USPTO's maintenance fee lookup

Maintenance fee events come from USPTO's own fee records. Its fee lookup asks for the patent number and the application number.

The Patent Finder CompaniesExpirationsCalculatorWatchlistPricing MethodologyCorrectionsLegalPrivacysupport@thepatentfinder.com Updated Nov 14, 2026 · includes USPTO assignment & status data published Nov 14, 2026 and grant & fee data published Nov 10, 2026 (weekly) Part of 137 Finder · © 2026 137 Finder LLC · Sources cited